USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: P50213 USC-OGP 2-DE database:  P50213 P50213 General information about the entry View entry in simple text format Entry name IDH3A_HUMAN Primary accession number P50213 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; EC=1.1.1.41; AltName: Full=Isocitric dehydrogenase subunit alpha; AltName: Full=NAD(+)-specific ICDH subunit alpha; Flags: Precursor;. Gene name Name=IDH3A Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0425: pI=5.60; Mw=40609 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0726: pI=5.65; Mw=37982 Cross-references UniProtKB/Swiss-Prot P50213; IDH3A_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name IDH3A_HUMAN Primary accession number P50213 Secondary accession number(s) D3DW83 Q9H3X0 Sequence was last modified on  October 1, 1996 (version 1) Annotations were last modified on  March 15, 2017 (version 171) Name and origin of the protein Description RecName: Full=Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; EC=1.1.1.41; AltName: Full=Isocitric dehydrogenase subunit alpha; AltName: Full=NAD(+)-specific ICDH subunit alpha; Flags: Precursor; Gene name Name=IDH3A Encoded on Name=IDH3A Keywords Acetylation; Alternative splicing; Complete proteome; Direct protein sequencing; Magnesium; Manganese; Metal-binding; Mitochondrion; NAD; Oxidoreductase; Phosphoprotein; Reference proteome; Transit peptide; Tricarboxylic acid cycle. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U07681; AAA85639.1; -; mRNA EMBL AL442090; CAC09449.1; -; mRNA EMBL CH471136; EAW99181.1; -; Genomic_DNA EMBL CH471136; EAW99182.1; -; Genomic_DNA EMBL BC021967; AAH21967.1; -; mRNA CCDS CCDS10297.1; -. [P50213-1]; . PIR S55282; S55282; . RefSeq NP_005521.1; NM_005530.2. [P50213-1]; . UniGene Hs.591110; -; . ProteinModelPortal P50213; -; . SMR P50213; -; . BioGrid 109645; 51; . IntAct P50213; 10; . MINT MINT-1148360; -; . STRING 9606.ENSP00000299518; -; . DrugBank DB00157; NADH; . iPTMnet P50213; -; . PhosphoSitePlus P50213; -; . SwissPalm P50213; -; . BioMuta IDH3A; -; . DMDM 1708399; -; . OGP P50213; -; . REPRODUCTION-2DPAGE IPI00030702; -; . EPD P50213; -; . MaxQB P50213; -; . PaxDb P50213; -; . PeptideAtlas P50213; -; . PRIDE P50213; -; . DNASU 3419; -; . Ensembl ENST00000299518; ENSP00000299518; ENSG00000166411. [P50213-1]; . GeneID 3419; -; . KEGG hsa:3419; -; . UCSC uc002bdd.4; human. [P50213-1]; . CTD 3419; -; . DisGeNET 3419; -; . GeneCards IDH3A; -; . HGNC HGNC:5384; IDH3A; . HPA HPA041465; -; . HPA HPA062971; -; . MIM 601149; gene; . neXtProt NX_P50213; -; . OpenTargets ENSG00000166411; -; . PharmGKB PA29632; -; . eggNOG KOG0785; Eukaryota; . eggNOG COG0473; LUCA; . GeneTree ENSGT00550000074918; -; . HOGENOM HOG000021113; -; . HOVERGEN HBG052080; -; . InParanoid P50213; -; . KO K00030; -; . OMA NQKQVTR; -; . OrthoDB EOG091G094X; -; . PhylomeDB P50213; -; . TreeFam TF105692; -; . BioCyc MetaCyc:ENSG00000166411-MONOMER; -; . Reactome R-HSA-71403; Citric acid cycle (TCA cycle); . SABIO-RK P50213; -; . ChiTaRS IDH3A; human; . GeneWiki IDH3A; -; . GenomeRNAi 3419; -; . PRO PR:P50213; -; . Proteomes UP000005640; Chromosome 15; . Bgee ENSG00000166411; -; . CleanEx HS_IDH3A; -; . ExpressionAtlas P50213; baseline and differential; . Genevisible P50213; HS; . GO GO:0005759; C:mitochondrial matrix; TAS:Reactome; . GO GO:0005739; C:mitochondrion; IDA:HPA; . GO GO:0043209; C:myelin sheath; IEA:Ensembl; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC; . GO GO:0000287; F:magnesium ion binding; IEA:InterPro; . GO GO:0051287; F:NAD binding; IEA:InterPro; . GO GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc; . GO GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome; . Gene3D 3.40.718.10; -; 1; . InterPro IPR019818; IsoCit/isopropylmalate_DH_CS; . InterPro IPR004434; Isocitrate_DH_NAD; . InterPro IPR024084; IsoPropMal-DH-like_dom; . Pfam PF00180; Iso_dh; 1; . SMART SM01329; Iso_dh; 1; . TIGRFAMs TIGR00175; mito_nad_idh; 1; . PROSITE PS00470; IDH_IMDH; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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